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'Man flu" is a derogatory term used to mock men for being “weak” by getting sick in the first place and it doesn’t actually matter if the symptoms are more severe or last longer. Men are being mocked because they are admitting that being sick actually impacts them.
Medically, yeah, knowing if there is a significant difference will most likely be helpful for treatment but that isn’t really relevant for a sexist insult.
I mean, haven’t we known for a long time women have better pain tolerance?