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Some genes only work when got from a female parent, or from a male parent: iirc, that is called “imprinting”.
Ttbomk, nobody knows why the effect happens.
Screwing with things for curiosity’s sake is fine,
so long as you are paying the price for the screwery, right?
I’ll bet that using only-male-chromosomes/genes for making new human lives will have some dire health-consequences for the new life.