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Bin Laden didn’t have a couple of thousand nukes at his disposal.
One of the differences is that Osama bin Laden was not the leader of any recognized state in the world whereas Putin is.
Putting a literal bullseye on another country’s leader would be seen as an act of war.
Also, the US is not currently in (direct) war with Russia while the US was with Osama’s group.
If you somehow killed him he would be replaced by someone who would be in a position of having to prove they were strong enough for the position.