Something about the regulations of these giant container ships has to change moving forward

Dedicated bus lanes can have multiple times the capacity in terms of moving people compared lanes that allow cars. Say you got a six lane road in the suburbs, convert the center lanes in each direction to dedicated bus lanes, then have a small median/curb separating the bus and car lanes on both sides. This will make buses faster than cars because of the lower congestion and incentive people to use them, making car congestion go down as well, because people who would otherwise drive are now on the bus.

City Nerd has a great channel focusing on stuff like this on YouTube and Nebula

Thanks! This is the closest thing I’ve seen on Lemmy to an r/AskHistorians thread, wish we had more of that

We do trials to determine if a new treatment is safe and effective. Let’s say you got a “miracle drug” that cures whatever disease you’re studying, but it is too toxic and kills patients over time. That drug may get hyped up in early development as a miracle cure, but you need to compare it to something else to be sure the toxicity seen is not driven by something unrelated. This is why it’s not ethical to run late stage trials without a standard of care or placebo control arm, because in this case the standard of care would be the better treatment option.

This concept is called equipoise, as in the two treatments are equally poised to provide benefit to patients at the beginning of the trial. Otherwise if you had enough data to know for certain your new therapy is better, then the trial is unnecessary and it should just be a regular medicine/submitted to a health authority for approval instead of wasting >$100 million dollars on another trial.

If you know your investigational therapy is better than a placebo or standard of care, then why do the trial? Just because something is new doesn’t mean it’s good