Israel will respond “quite forcefully” to Iran’s Tuesday missile assault, potentially going after the country’s nuclear facilities and going after Iranian Supreme Leader Ali Khamenei himself, retired U.S. Army Lt. Gen. Keith Kellogg, a national security adviser under former President Donald Trump and Vice President Mike Pence, said Tuesday.

Israeli Prime Minister Benjamin Netanyahu has told the world that he “‘we have given you repeated opportunities to bring this thing to a conclusion,’” and as that hasn’t happened, “I think he’s going for the killing,” Kellogg told Fox News.

“He’s going to respond quite forcefully,” Kellogg said. “I think if I was Iran I would say I think he’s going to make a key shot at the nuclear facilities and going after the supreme leader.”

Tuesday’s air attack, he added, will set “everything in motion for a much wider war in the Middle East,” as the Israelis have decided that they’ve had enough.

“It’s probably about time,” said Kellogg. This needs to be brought to some type of conclusion. If we are not going to help them conclude it, they are going to have to do it on their own. That’s probably what they are trying to do."